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LHPG Presentations at CROI
Added: Tuesday 16th February 2010
Several members of the Liverpool HIV Group had poster and/or oral presentations accepted for the 17th Conference on Retroviruses and Opportunistic Infection. PDFs of these posters and presentation have been added to the  |
New format interaction charts
Added: Tuesday 6th October 2009
The format of the interaction charts has been changed to make searching for interactions easier and to distinguish between those interactions for which data exists (“referenced interactions”) and those which are predicted based on routes of metabolism and elimination (“theoretical interactions”).
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New fact sheets available
Added: Monday 28th September 2009
New fact sheets have been added to the Pharmacology Resources section of the website. These fact sheets contain information on the chemical nature and structure of a drug, its key pharmacokinetic parameters and its metabolism and distribution.
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New drugs added to interaction charts
Added: Monday 30th March 2009
There are several additions to the interactions charts – both new drugs and a new class.
As well as introducing new drugs to existing classes, we have introduced a new class of drugs – Heart Failure Agents – which includes ACE inhibitors, angiotensin II receptor antagonists and diuretics.
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Personalised, printable reports now available for interaction charts
Added: Friday 3rd October 2008
NEW - personalised, printable reports
We have launched a new feature for the interactive charts that allows you to create and save a summary of your chosen interactions in pdf format. Just make your drug selection in the usual way and, when the table of interactions is displayed, you will see a new option to generate a personalised report (please note that this feature is limited to 25 drugs per report).
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New Interactive Charts and Updated Printable Charts
Added: Thursday 4th September 2008
New Interactive Charts for Entry and Integrase Inhibitors
Interactive charts for Maraviroc and Raltegravir are now available. These charts are less extensive than the PI and NNRTI charts and have been compiled from the Summary of Product Characteristics, Prescribing Information, meeting abstracts and full papers.
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New Drugs for the Interaction Charts
Added: Friday 29th August 2008
There have been some changes and additions to the Interaction Charts over the last few weeks.
On the Protease Inhibitor chart, amprenavir has been replaced by fosamprenavir. The interactions are essentially the same, apart from a few amber interactions that were due to the alcohol content of amprenavir oral solution and are not relevant for fosamprenavir.
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Varenicline Added to Charts
Added: Thursday 20th March 2008
The smoking cessation drug varenicline (Champix®, Chantix®) has been added as a row to the interactive charts and will be included on the printed charts when they are next updated. Drug interactions are not expected with varenicline as it has been shown in vitro not to inhibit or induce cytochrome P450 enzymes.
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Additional information on hormonal contraceptives.
Added: Thursday 28th February 2008
Information on hormonal contraceptives is listed on the charts in the steroid section under ethinylestradiol and progesterone/progestogens. The information available is predominantly for daily oral contraceptives, but other routes and frequencies of administration are now available.
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Updates to Interaction Charts
Added: Wednesday 28th November 2007
The following drugs have been added as rows to the interaction charts:
Etravirine – new NNRTI
Maraviroc – new entry inhibitor
Elvitegravir – new integrase inhibitor
Raltegravir – new integrase inhibitor A summary and description have been provided for those interactions where studies have been performed.
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Updates to NNRTI Charts
Added: Friday 1st June 2007
The NNRTI charts have been updated to reflect changes made in the wording or data presented in the most recent versions of the European Summaries of Product Characteristics and the US Prescribing Information.
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Updates to PI charts - darunavir added
Added: Friday 1st June 2007
Darunavir (Prezista, TMC114) has now been added to the interaction charts in full. Currently only interactions detailed in the Summary of Product Characteristics or Prescribing Information are referenced.
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Tipranavir now available on the Interaction Charts
Added: Tuesday 7th November 2006
Tipranavir (Aptivus), a non-peptidic protease inhibitor, was recently licensed in Europe (FDA approval was granted earlier this summer). We have now completed our evaluation of the literature and have added tipranavir interactions to the Interaction Charts.
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Presentation - Medscape Webcast. Optimizing Antiretroviral Therapy for HIV: Key Pharmacologic Concerns
Added: Friday 21st July 2006
Medscape Web Conference
Optimizing Antiretroviral Therapy for HIV: Key Pharmacologic Concerns.
Presenters: David Back, PhD, and Marta Boffito, MD, PhD In this recent CME/Pharmacist CE program, David Back and Marta Boffito explain pharmacologic information of key importance to HIV clinicians such as drug-drug interactions, adverse effects, TDM, inhibitory quotients, pharmacogenomics, and double-boosted PIs.
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Presentations from the 7th HIV Pharmacology Workshop
Added: Wednesday 14th June 2006
The 7th International Workshop on Clinical Pharmacology of HIV Therapy was held this year in Lisbon. Several members of LHPG attended and presented data. Oral presentations were given by Laura Dickinson, Sara Gibbons and Saye Khoo, and poster presentations were given by Laura Else and Wai San Kwan.
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Interaction Charts - antimalarial drugs revised and expanded.
Added: Friday 12th May 2006
The Drug Interaction Charts have been revised to include extra antimalarial drugs and additional information on existing drugs.
The following antimalarial drugs have been added to the interaction charts:
- Amodiaquine
- Artemesinins (Artemether, Artesunate)
- Primaquine
- Quinine
- Sulfadoxine/Pyrimethamine
Further details on the nature of interactions with atovaquone, dapsone*, halofantrine, lumefantrine and proguanil have been added.
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Poster Presentations from 13th CROI Meeting.
Added: Friday 28th April 2006
Presentations from the recent meeting in Denver by members of the Liverpool HIV Pharmacology Group have now been added to the About Us section of this website. The posters are available as Acrobat pdf files and contain a link to the abstract from the Conference website.
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